Complex interventions — PRISMA statement

PRISMA Complex Interventions (PRISMA-CI)

The PRISMA extension for systematic reviews of complex interventions was published in 2017. It provides provide guidance to promote consistency and improve the reporting and usability of systematic reviews on complex interventions (i.e. interventions which have multiple components (intervention complexity) and complicated/multiple causal pathways, feedback loops, synergies, and/or mediators and moderators of effect (pathway complexity)).

Key documents

Statement paper: Guise JM, Butler ME, Chang C, Viswanathan M, Pigott T, Tugwell P; Complex Interventions Workgroup. AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist. J Clin Epidemiol. 2017;90:43-50. doi: 10.1016/j.jclinepi.2017.06.016.
Explanation and Elaboration paper: Guise JM, Butler M, Chang C, Viswanathan M, Pigott T, Tugwell P; Complex Interventions Workgroup. AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation. J Clin Epidemiol. 2017;90:51-58. doi: 10.1016/j.jclinepi.2017.06.017.